Evaluation of Skin Irritation Level and Effectiveness of Foot Sleeping Mask Containing Tengkawang Fat in Nanostructured Lipid Carriers System

Ayu Fidayanti; Fransisca Dita Mayangsari; Elasari Dwi Pratiwi

doi:10.35451/jfm.v7i2.2608

Authors

Ayu Fidayanti Universitas Muhaammadiyah Lamongan
Fransisca Dita Mayangsari Universitas Muhammadiyah Lamongan
Elasari Dwi Pratiwi Universitas Muhammadiyah Lamongan

DOI:

https://doi.org/10.35451/jfm.v7i2.2608

Keywords:

Foot Sleeping Mask, Tengkawang Fat, NLC

Abstract

One of the export commodities from the Non-Timber Forest Products (NTFP) group is tengkawang fruit. This fruit can be processed into fat which has properties similar to cocoa butter. The advantage of this fat compared to cocoa butter is that the price is relatively cheaper. However, the use of tengkawang fat in cosmetics is not widely known. Therefore, researchers are interested in developing cosmetic products based on tengkawang fat to treat xerosis of the feet. To increase occlusivity, tengkawang fat is formulated into an NLC (Nanostructured Lipid Carriers) system. In this research, a foot sleeping mask product was made containing NLC tengkawang fat with the addition of gel (to improve viscosity) and sweet orange oil (to improve aroma). The aim of this research was to determine the irritation skin level and effectiveness of moisturizing the skin of the soles of the feet from a foot sleeping mask containing NLC tengkawang fat. The results of the physical characteristics test show that the foot sleeping mask made meets the desired specifications. The results of skin irritation tests with 35 panelists showed that there was no redness or edema on the panelists' skin during 24, 48 and 72 hours of observation. The results of the moisture effectiveness test showed that the average moisture content of the soles of the panelists' feet on day 0 was 34.531%, while on day 28 (4 weeks) it was 42.815%. There was an increase in humidity of 8.284% during 4 weeks of use. The conclusion of this research is that a foot sleeping mask containing Tengkawang fat NLC can increase the moisture of the skin of the soles of the feet by 8.284% during 4 weeks of use.

Downloads

Download data is not yet available.

References

M. Nuryanti And A. Suwarno, “Persepsi Masyarakat Dusun Melayang Terhadap Potensi Buah Tengkawang (Shorea Spp) Sebagai Salah Satu Buah Langka Bernilai Ekonomi Dari Kalimantan Barat,” Sos. Horiz. J. Pendidik. Sos., Vol. 8, No. 1, Pp. 127–137, 2021, Doi: 10.31571/Sosial.V8i1.3256.

J. Parker, R. Scharfbillig, And S. Jones, “Moisturisers For The Treatment Of Foot Xerosis: A Systematic Review,” J. Foot Ankle Res., Vol. 10, No. 1, Pp. 1–10, 2017, Doi: 10.1186/S13047-017-0190-9.

F. Sari, D. Nurhadi Illian, And O. Sylvia Br. Ginting, “Formulasi Krim Minyak Alpukat (Avocado Oil) Dan Efektivitasnya Terhadap Xerosis Pada Tumit Kaki,” Forte J., Vol. 2, No. 2, Pp. 129–136, 2022, Doi: 10.51771/Fj.V2i2.393.

R. Repiani, “Formulasi Sediaan Foot Care Dari Bahan Alam,” Parapemikir J. Ilm. Farm., Vol. 10, No. 2, P. 91, 2021, Doi: 10.30591/Pjif.V10i2.2140.

F. Diba, A. Afra, And G. E. Tavita, “Formulasi Dan Evaluasi Handbody Lotion Berbahan Dasar Lemak Tengkawang (Illipe Butter),” J. Hutan Lestari, Vol. 11, No. 3, P. 700, 2023, Doi: 10.26418/Jhl.V11i3.71156.

M. Elmowafy And M. M. Al-Sanea, “Nanostructured Lipid Carriers (Nlcs) As Drug Delivery Platform: Advances In Formulation And Delivery Strategies,” Saudi Pharm. J., Vol. 29, No. 9, Pp. 999–1012, 2021, Doi: 10.1016/J.Jsps.2021.07.015.

C. Viegas, A. B. Patrício, J. M. Prata, A. Nadhman, P. K. Chintamaneni, And P. Fonte, “Solid Lipid Nanoparticles Vs. Nanostructured Lipid Carriers: A Comparative Review,” Pharmaceutics, Vol. 15, No. 6, 2023, Doi: 10.3390/Pharmaceutics15061593.

R. D. Aulya And N. Ermawati, “Formulasi Dan Uji Fisikokimia Gel Sleeping Mask Ekstrak Kulit Buah Naga Merah Dengan Variasi Gelling Agent Hydroxypropyl Methly Cellulose (Hpmc),” J. Med. Nusant., Vol. 1, No. 2, Pp. 40–53, 2023.

F. D. Mayangsari, Djati Wulan Kusumo, And Zurotul Muarifah, “Uji Karakteristik Fisik Dan Hedonik Dari Antiaging Sleeping Mask Dengan Ekstrak Kulit Buah Delima Merah,” J. Ilm. Manuntung, Vol. 8, No. 2, Pp. 302–310, 2022, Doi: 10.51352/Jim.V8i2.640.

R. A. Fachriani, P. G. A. Safitri, U. Chasanah, And F. D. Mayangsari, “Pengaruh Waktu Pengadukan Terhadap Karakteristik Fisik Nanostructured Lipid Carriers Menggunakan Metode High Shear Homogenization,” Maj. Farmasetika, Vol. 8, No. 1, P. 95, 2022, Doi: 10.24198/Mfarmasetika.V8i1.41860.

F. D. Mayangsari, T. Erawati, W. Soeratri, And N. Rosita, “Karakteristik Dan Stabilitas Fisik Nlc-Koenzim Q10 Dalam Sleeping Mask Dengan Minyak Nilam,” J. Farm. Dan Ilmu Kefarmasian Indones., Vol. 8, No. 2, P. 178, 2021, Doi: 10.20473/Jfiki.V8i22021.178-186.

F. D. Mayangsari, P. G. A. Safitri, U. Khasanah, And K. Khotimah, “Uji Karakteristik Fisik Dan Hedonik Dari Aromatherapy Hand Cream Yang Mengandung Minyak Melati,” Med. Sains J. Ilm. Kefarmasian, Vol. 7, No. 2, Pp. 17–22, 2022, Doi: 10.37874/Ms.V7i2.325.

V. Rosari, N. Fitriani, And F. Prasetya, “Optimasi Basis Gel Dan Evaluasi Sediaan Gel Anti Jerawat Ekstrak Daun Sirih Hitam (Piper Betle L. Var Nigra),” Proceeding Mulawarman Pharm. Conf., No. April 2021, Pp. 204–212, 2021.

L. Badriyah, E. N. N. Asih, S. N. Ni’amah, R. H. Ningrum, Y. Mardiyanti, And D. R. Wulansari, “Penambahan Ekstrak Lamun (Enhalus Acoroides) Dan Gonad Bulu Babi (Diadema Setosum) Sebagai Formulasi Sediaan Moisturizer Body Lotion,” J. Pengolah. Has. Perikan. Indones., Vol. 26, No. 1, Pp. 97–106, 2023, Doi: 10.17844/Jphpi.V26i1.44880.

N. Komang Sumarni And J. Raya Kampus Unud Jimbaran Badung-Bali, “Review Artikel?: Uji Iritasi Sediaan Topikal Dari Tumbuhan Herbal,” J. Jejaring Mat. Dan Sains, Vol. 4, No. 1, P. 13, 2022, [Online]. Available: Https://Doi.Org/10.36873/Jjms.2021.V4.I1.703

D. Aryantini, I. Kristianingsih, E. Kurniawati, And A. R. Lanuru, “Sifat Fisik Dan Uji Iritasi Akut Dermal Soothing Gel Kombinasi Lidah Buaya Dan Buah Naga,” Parapemikir J. Ilm. Farm., Vol. 9, No. 1, P. 7, 2020, Doi: 10.30591/Pjif.V9i1.1671.

R. Suharsanti And L. W. Ariyani, “Efek Pelembab Kulit Sediaan Shooting Gel Kombinasi Daun Lidah Buaya Dan Buah Anggur,” J. Farm. Sains Indones., Vol. 1, No. 1, Pp. 25–30, 2018, [Online]. Available: Http://Journal.Akfarnusaputera.Ac.Id/

R. Rakhmawati, A. N. Artanti, And N. Afifah, “Pengaruh Variasi Konsentrasi Tamanu Oil Terhadap Uji Stabilitas Fisik Sediaan Body Lotion,” Annu. Pharm. Conf., Vol. 4, No. 1, Pp. 53–65, 2019.

A. F. Tsabitah, A. K. Zulkarnain, M. S. H. Wahyuningsih, And D. A. A. Nugrahaningsih, “Optimasi Carbomer, Propilen Glikol, Dan Trietanolamin Dalam Formulasi Sediaan Gel Ekstrak Etanol Daun Kembang Bulan (Tithonia Diversifolia),” Maj. Farm., Vol. 16, No. 2, P. 111, 2020, Doi: 10.22146/Farmaseutik.V16i2.45666.

European Directorate For The Quality Of Medicines & Healthcare Of The Council Of Europe (Edqm), “Guidance On,” Guid. Essent. Oils Cosmet. Prod., 2016.

R. Aryani, A. Anggriani, M. Hartiwan, And S. Nurlela, “Uji Efektivitas Krim Pelembab Yang Mengandung Gel Daun Lidah Buaya ( Aloe Vera Linn .) Dan Etil Vitamin C,” Vol. 2, No. 1, Pp. 52–61.