Administration of Etlingera hemisphaerica Fruit Juice on the Recovery of Glucose Levels Due to HgCl₂ Treatment in Mice (Mus musculus )

Davina Shava Ferlia; Aceng Ruyani; Deni Parlindungan; Annisa Puji Astuti; Afrizal Mayub

doi:10.35451/20j17j97

Authors

Davina Shava Ferlia Universitas Bengkulu
Aceng Ruyani Pendidikan IPA FKIP Universitas Bengkulu
Deni Parlindungan Pendidikan IPA FKIP Universitas Bengkulu
Annisa Puji Astuti Pendidikan IPA FKIP Universitas Bengkulu
Afrizal Mayub Pendidikan IPA FKIP Universitas Bengkulu

DOI:

https://doi.org/10.35451/20j17j97

Keywords:

Etlingera hemisphaerica, HgCl₂, Kadar Glukosa, Mus musculus, MSBE

Abstract

Background: Fruit juice is highly needed nowadays due to its effectiveness as a source rich in antioxidants.Research Objective: This study aims to reduce glucose levels caused by the administration of HgCl₂, which is neurotoxic and cytotoxic, capable of damaging pancreatic β-cells that produce insulin. Etlingera hemisphaerica was utilized as a potential solution because it contains compounds such as terpenoids, flavonoids, phenols, and polyphenols that can lower glucose levels by maintaining the normal function of pancreatic β-cells. Method: This study applied a true experimental method with a pretest-posttest control group design, involving measurements taken before and after treatment. The subjects were divided into three test groups K1, K2, and K3 each consisting of three Mus musculus , with a total of nine mice. Results: The administration of Etlingera hemisphaerica Fruit Fresh Drink (MSBE) did not show a significant effect in reducing blood glucose levels in Mus musculus induced with HgCl₂. Conclusion: The secondary metabolites contained in E. hemisphaerica have not yet been able to repair or maintain blood glucose levels under conditions of damage caused by HgCl₂ exposure.

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