Antifungal Potential of Pineapple Rind and Foliage Crown (Ananas comosus L. Merr) Waste Extracts Against Dermatophyte and Non-Dermatophyte Fungi

Anindita Riesti Retno Arimurti; Baterun Kunsah; Dita Artanti; Fitrotin Azizah; Yety  Eka Sispita Sari

doi:10.35451/73e7qm59

Authors

Anindita Riesti Retno Arimurti Diploma of Medical Laboratory Technology, Faculty of Health Science, Universitas Muhammadiyah Surabaya, Surabaya, Indonesia https://orcid.org/0000-0002-5446-0462
Baterun Kunsah Bacelor of Medical Laboratory Technology, Faculty of Health Science, Universitas Muhammadiyah Surabaya, Surabaya, Indonesia https://orcid.org/0000-0002-5446-0462
Dita Artanti Diploma of Medical Laboratory Technology, Faculty of Health Science, Universitas Muhammadiyah Surabaya, Surabaya, Indonesia https://orcid.org/0000-0002-5852-3379
Fitrotin Azizah Diploma of Medical Laboratory Technology, Faculty of Health Science, Universitas Muhammadiyah Surabaya, Surabaya, Indonesia https://orcid.org/0000-0003-0388-5716
Yety Eka Sispita Sari Diploma of Medical Laboratory Technology, Faculty of Health Science, Universitas Muhammadiyah Surabaya, Surabaya, Indonesia https://orcid.org/0000-0002-5446-0462

DOI:

https://doi.org/10.35451/73e7qm59

Keywords:

Ananas comosus L. Merr, Aspergillus niger, Dermatophyte, Mycosis, non-dermatophyte, Trichophyton rubrum

Abstract

Background: Fungal infections (mycoses) are common health problems in Indonesia, where tropical climatic conditions favor fungal growth. These infections are generally classified into dermatophytosis and non-dermatophytosis and are commonly treated using synthetic antifungal agents such as ketoconazole, which may cause adverse effects. Therefore, safer natural alternatives are needed. Pineapple rind and foliage crown (Ananas comosus L. Merr), which are typically discarded as agricultural waste, contain bioactive compounds with potential antifungal activity, including flavonoids, alkaloids, saponins, and tannins. Purpose: This study aimed to evaluate the antifungal activity of ethanol extracts from pineapple rind and foliage crown waste against Trichophyton rubrum and Aspergillus niger. Methods: An experimental study was conducted using the Kirby–Bauer disc diffusion method with extract concentrations of 25%, 50%, and 75%, along with negative (0%) and positive (ketoconazole) controls. Results: Both pineapple rind and foliage crown extracts inhibited the growth of T. rubrum and A. niger. The 75% concentration exhibited the largest inhibition zones, indicating the highest antifungal effectiveness. Conclusion: These findings suggest that pineapple rind and foliage crown waste have potential as natural antifungal agents.

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