SEDIAAN SALEP EKSTRAK DAUN KELOR (MORINGA OLEIFERA LAM) SEBAGAI PENYEMBUHAN LUKA BAKAR TOPIKAL PADA KELINCI (ORYCTOLAGUS CUNICULUS)

  • Wahyudi Wahyudi Institut Kesehatan Deli Husada
  • Hanna Agustina Institut Kesehatan Deli Husada Delitua
Keywords: ekstrak daun kelor, luka bakar, salep

Abstract

Burns is a form of tissue damage caused by contact with a heat source such as fire, hot water, chemicals, electricity and radiation. Burns occur on the skin, mucous membranes, respiratory tract and gastrointestinal tract. Actions that can be performed on burns is to provide local treatment with the aim to get relief as quickly as possible. One of the traditional medicines used empirically society as burn treatment is by softening Moringa leaves Moringa leaves and placed on the affected part of the wound. This tudy aim to determine the effect of healing of burns using Moringa leaf extract ointment and to determine the concentration of Moringa leaf extract in the ointment preparation is most effective in the healing of burns. Experimental method. Result of this study show phytochemical screening results indicate the presence of alkaloids, flavonoids, saponins, tannins. observations of Moringa leaf extract ointment preparation during storage of 7 days showed that the formula has a good appearance, homogeneous, smell and color. Diameter burns decline, a group of rabbits treated with the ointment extract of the leaves of Moringa 6% that is 0.9 cm, a group of rabbits given ointment extract of the leaves of Moringa 8% ie 0.91 cm, a group of rabbits given ointment extract of Moringa leaves 10% that is 0.95 cm, Bioplacenton® namely the group given 0.89 cm, while the group of rabbits given distilled water of 0.77 cm. Conclusion of this study show that extracts leaves of Moringa had an effect in the healing of burns. Ointments Moringa leaf extract 10% of the most effective in the healing of burns and has a greater potential than the Bioplacenton®. Burn healing effect on the concentration of 8% and 6% more effective than the negative comparison.

Downloads

Download data is not yet available.

References

Aminah, S., 2015. Kandungan Nutrisi dan Sifat Fungsional Tanaman Kelor (Moringa oleifera Lam.), Balai Pengkajian Teknologi Pertanian Jakarta.

Ananto, J.F., Herwanto, S.E., Nugrahandhini, B.N., Najwa, C.Y., Abidin, Z.M., Suswati, I., 2015. Gel Daun Kelor sebagai Antibiotik Alami Pada Pseudomonas aeruginosa secara In Vivo, Hal 3, Tesis Fakultas Kedokteran, Universitas Muhammadiyah Malang.

Anief, M., 2006. Ilmu Meracik Obat Teori dan Praktek, Hal 52-55, Gadjah MadaUniversity Press, Yogyakarta.

Anonim. 1979. Farmakope Indonesia. Edisi ketiga. Jakarta: Departemen Kesehatan.

Depkes RI. (1995). Materia Medika Indonesia. Jilid VI. Jakarta: Departemen Kesehatan RI. Halaman 297-307, 321, 325, 333-337.

Farnsworth, N.R. (1966). Biological and Phytochemical Screening of Plant. Journal of Pharmaceutical Science. 55(3) : 262-265.

Hanani, E. Analisis Fitokimia, Hal 10, Dalam : Buku Kedokteran. Jakarta : EGC, 2015.

Hardiyanthi, F., 2015. Pemanfaatan Aktivitas Antioksidan Ekstrak Daun Kelor (Moringa oleifera) dalam Sediaan Hand and Body Cream, Hal 7-8, Tesis Fakultas Sains dan Teknologi, Universitas Islam Negeri Syarif Hidayatullah Jakarta.

Izziati, Z., 2015. Efektivitas penyembuhan luka bakar salep ekstrak etanol daun senggani (Melastoma malabathricum L.) pada tikus (Rattus novergicus) jantan galur wistar, Fakultas Kedokteran, Universitas Tanjungpura Pontianak.

Published
2018-10-15
How to Cite
Wahyudi, W., & Agustina, H. (2018). SEDIAAN SALEP EKSTRAK DAUN KELOR (MORINGA OLEIFERA LAM) SEBAGAI PENYEMBUHAN LUKA BAKAR TOPIKAL PADA KELINCI (ORYCTOLAGUS CUNICULUS). JURNAL FARMASIMED (JFM), 1(1), 21-24. https://doi.org/10.35451/jfm.v1i1.91