Evaluation of Creatinine Levels as an Indicator of Kidney Function in Diabetes Mellitus Patients at RSU Haji Medan
DOI:
https://doi.org/10.35451/mmj.v2i2.2665Keywords:
Creatinine, Diabetes Mellitus, Kidney Function, Creatine, Type 2 DMAbstract
Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic disorder that can lead to serious complications, including impaired kidney function. Serum creatinine is one of the key parameters used to evaluate renal function in diabetic patients, as its concentration remains relatively stable and is not significantly influenced by protein intake. This study aimed to assess the profile of serum creatinine levels in patients with T2DM at RSU Haji Medan as an early indicator of potential renal complications. A descriptive study with a cross-sectional design was conducted. The study involved a total of 25 hospitalized T2DM patients who underwent serum creatinine testing. All available medical records were included as the sample. Out of 25 patients, 15 (60%) showed creatinine levels within the normal range, while 10 patients (40%) had elevated creatinine levels. The mean creatinine concentration was 2.42 mg/dL in male patients and 0.85 mg/dL in female patients. The findings indicate that a portion of T2DM patients have already experienced reduced kidney function. Regular monitoring of serum creatinine is essential for early detection and prevention of diabetic kidney complications.
References
Armaningrum TP, Budiharjo T. Gambaran Kadar Kreatinin Serum Pada Pasien Rawat Inap Yang Didiagnosis Diabetes Melitus Tipe 2. Jar Lab Medis. 2022;4(1):7–15.
Mishra KP, Mawar A, Kare PK, Verma N. Relationship Between Fasting Blood Glucose, Serum Urea, Serum Creatinine and Duration of Diabetes in Type-2 Diabetic Patients. Flora and Fauna. 2015;21(1):127–32.
Trihartati V. Gambaran Kadar Ureum dan Kreatinin Serum pada Pasien Diabetes Melitus Tipe-2 di Rumah Sakit Santa Maria Pekanbaru. J Sains dan Teknol Lab Med. 2020;4(2):44–53.
Tipe M, Rsud DI, Periode J. KREATININ SERUM PADA PENDERITA DIABETES. 2024;
Jumadewi A, Rahmayanti R, Fajarna F, Krisnawati WE. Kadar kreatinin serum pasien diabetes mellitus tipe 2 pada kelompok usia 40 tahun keatas. J SAGO Gizi dan Kesehat. 2022;4(1):52.
I Gusti Ayu Putu Widia Satia Padma, Ida Ayu Made Sri Arjani INJ. Gambaran Kadar Kreatinin Serum Pada Penderita Diabetes Mellitus Tipe 2 Di Rumah Sakit Umum Pusat Sanglah Denpasar. Meditory J Med Lab. 2018;5(2):107–17.
Karno N, Mahtuti EY, Faisal, Basyaruddin M. Hubungan Kadar Kreatinin Dan Lama Mengkonsumsi Obat Diabetes Pada Penderita Dm Tipe 2. J Kesehat Tambusai. 2023;4(4):4981–7.
Gu J, Zang W, Liu B, Li L, Huang L, Li S, et al. Evaluation of digital PCR for detecting low-level EGFR mutations in advanced lung adenocarcinoma patients: A cross-platform comparison study. Oncotarget. 2017;8(40):67810–20.
Giandalia A, Giuffrida AE, Gembillo G, Cucinotta D, Squadrito G, Santoro D, et al. Gender differences in diabetic kidney disease: Focus on hormonal, genetic and clinical factors. Int J Mol Sci. 2021;22(11).
Melani EM, Anggita Kartikasari Program Studi Analis Kesehatan L, Piksi Ganesha Jl Jend Gatot Subroto No P. Gambaran Kadar Ureum Kreatinin Pada Penderita Diabetes Tipe-2 Di Rumah Sakit Otika Medika Serang Banten. J INFOKES-Politeknik Piksi Ganesha. 2020;4(2):12–22.
Thomas NJ, Shields BM, Besser REJ, Jones AG, Rawlingson A, Goodchild E, et al. The impact of gender on urine C-peptide creatinine ratio interpretation. Ann Clin Biochem. 2012;49(4):363–8.
Kashima S, Inoue K, Matsumoto M. Low creatinine levels in diabetes mellitus among older individuals: the Yuport Medical Checkup Center Study. Sci Rep [Internet]. 2021;11(1):1–8. Available from: https://doi.org/10.1038/s41598-021-94441-9
Annisa Puteri Ayudya, Sri Wahyunie FNR. DESKRIPSI KADAR KREATININ PENDERITA DIABETES MELITUS TIPE II DI RUMAH SAKIT UMUM DAERAH ABDOEL WAHAB SJAHRANIE SAMARINDA PADA TAHUN 2021-2023. 2024;11(11):2194–201.
DAVIES L, ERROL G. WILMSHURST, AIDAN MCELDUFF JG, CLIFTON-BLIGH P, GREGORY R. FULCHER. Creatinine Clearance , and Albuminuria in Patients With Type 2 Diabetes. Diabetes Care. 2001;24(10).
Sartika F, Purbayanti D, Safitri D. Gambaran Laju Filtrasi Glomerulus Pada Penderita Diabetes Mellitus Tipe 2 Di RSUD Dr. Doris Sylvanus Palangka Raya. J Surya Med. 2018;3(2):13–22.
Karar T, Alniwaider RAR, Fattah MA, Al Tamimi W, Alanazi A, Qureshi S. Assessment of microalbuminuria and albumin creatinine ratio in patients with type 2 diabetes mellitus. J Nat Sci Biol Med. 2015;6:S89–92.
Norris KC, Smoyer KE, Rolland C, Van Der Vaart J, Grubb EB. Albuminuria, serum creatinine, and estimated glomerular filtration rate as predictors of cardio-renal outcomes in patients with type 2 diabetes mellitus and kidney disease: A systematic literature review. BMC Nephrol. 2018;19(1):1–13.
Okta Amalia R, Sulpha Siregar S, Febriyani E, Syailendra A, Kesehatan Palembang P. Gambaran Kadar Kreatinin Pada Penderita Hipertensi Di Rumah Sakit Islam Siti Khadijah Palembang Description of Creatinine Levels on Hypertension Patients At Siti Khadijah Islamic Hospital Palembang. JMLS) J Med Lab Sci. 2023;3(2):2023.
Gu L, Huang L, Wu H, Lou Q, Bian R. Serum uric acid to creatinine ratio: A predictor of incident chronic kidney disease in type 2 diabetes mellitus patients with preserved kidney function. Diabetes Vasc Dis Res. 2017;14(3):221–5.
Ahat F. Korelasi Kadar HbA1c Dengan Kadar Kreatinin Pada Pasien Diabetes Melitus Kronis. J Muhammadiyah Med Lab Technol. 2023;6(2):178–83.
Downloads
Published
Issue
Section
License
Copyright (c) 2025 Herlina Herlina
This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright in each article is the property of the Author.
